4 results found Sort:

AlexandrovLab
SigProfilerExtractor AlexandrovLab
52
154
bsd-2-clause
22
SigProfilerExtractor allows de novo extraction of mutational signatures from data generated in a matrix format. The tool identifies the number of operative mutational signatures, their activities in e...
bioinformatics cancer-genomics somatic-variants mutation-analysis mutational-signatures
Created 2018-08-30
450 commits to master branch, last one 6 months ago
ShixiangWang
sigminer ShixiangWang
19
147
other
2
🌲 An easy-to-use and scalable toolkit for genomic alteration signature (a.k.a. mutational signature) analysis and visualization in R https://shixiangwang.github.io/sigminer/reference/index.html
r cnv dbs nmf sbs indel easy-to-use bayesian-nmf visualization bioinformatics nmf-extraction cancer-research somatic-variants cosmic-signatures somatic-mutations signature-extraction copynumber-signatures mutational-signatures
Created 2018-12-30
1,261 commits to master branch, last one about a month ago
AlexandrovLab
SigProfilerMatrixGenerator AlexandrovLab
37
101
bsd-2-clause
23
SigProfilerMatrixGenerator creates mutational matrices for all types of somatic mutations. It allows downsizing the generated mutations only to parts for the genome (e.g., exome or a custom BED file)....
bioinformatics cancer-genomics somatic-variants mutation-analysis mutational-signatures
Created 2018-08-27
312 commits to master branch, last one 14 days ago
FunGeST
Palimpsest FunGeST
19
69
unknown
8
An R package for studying mutational signatures and structural variant signatures along clonal evolution in cancer.
r nmf genomics clonality driver-events visualization bioinformatics nmf-extraction cancer-genomics cancer-research tumor-evolution somatic-mutations tumor-heterogeneity signature-extraction structural-variation mutational-signatures bioinformatics-analysis structural-variant-signatures
Created 2018-03-12
232 commits to master branch, last one 6 months ago